Xp (short arm) genes: Deletions or interruptions of critical areas of the short-arm out of the X chromosome (Xp11, Xp22.1-21.3) was indeed revealed in colaboration with gonadal dysgenesis and prienorrhea.

Zfx (X-linked zinc thumb proteins): Located on Xp22.1-21.step three, so it gene encodes a widely indicated necessary protein away from unknown form. Zfx “knockout” mice are short, shorter rich, as well as have less germ cell number throughout the ovaries and you can testes.

USP9X gene (ubiquitin-certain protease nine gene): It’s situated on Xp11.4, and its device is extensively expressed a number of Problemas de facturação cherry blossoms architecture. Inside Drosophila, USP9X is required to possess eyes invention and you may oogenesis, but its role from inside the human gonadal development try uncertain.

Xq (long arm) genes: Data regarding terminal deletions and you will autosomal translocations produced information regarding the new significance of numerous section found on the long-arm of X-chromosome. They have been Xq13-21, Xq22-twenty five, and you will Xq26-28. Ler mais